BDBM5686 2-amino-5-thio-substituted thiazole 35::[5-[[[5-tert-Butyl-2-oxazolyl]methyl]thio]-2-thiazolyl]benzyl Carbamate::benzyl N-(5-{[(5-tert-butyl-1,3-oxazol-2-yl)methyl]sulfanyl}-1,3-thiazol-2-yl)carbamate

SMILES CC(C)(C)c1cnc(CSc2cnc(NC(=O)OCc3ccccc3)s2)o1

InChI Key InChIKey=AVZTYQBOJJCITC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 5686   

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandPNGBDBM5686(benzyl N-(5-{[(5-tert-butyl-1,3-oxazol-2-yl)methyl...)
Affinity DataIC50: 150nMAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2005
Entry Details Article
PubMed