BDBM570030 (+/−)-[2-(3,5-difluoro-4-{[3-(6-methylpyridazin-4-yl)-1H-pyrrolo[2,3-b]pyridin-4-yl]oxy}anilino)-5-fluoro-5,6-dihydro-4H-1,3-oxazin-5-yl]methanol::US11427578, Example 203

SMILES Cc1cc(cnn1)-c1c[nH]c2nccc(Oc3c(F)cc(NC4=NCC(F)(CO)CO4)cc3F)c12

InChI Key InChIKey=VSDOMIBNBJYOLB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 570030   

TargetSerine/threonine-protein kinase TBK1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM570030((+/−)-[2-(3,5-difluoro-4-{[3-(6-methylpyrida...)
Affinity DataIC50: 1.06E+4nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into either a black low volume 384 well microtiter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
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