BDBM570085 US11427591, Compound 119

SMILES Cc1cn(cn1)-c1cc(Nc2noc3c(C#Cc4cnc5cccnn45)c(C)ccc23)cc(c1)C(F)(F)F

InChI Key InChIKey=UXCYPLDDSDGGSU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 570085   

TargetEpithelial discoidin domain-containing receptor 1(Human)
Insilico Medicine Ip

US Patent
LigandPNGBDBM570085(US11427591, Compound 119)
Affinity DataIC50: 106nMAssay Description:The activity of the inhibitor compounds against DDR1 and DDR2 was tested using KinaseProfiler (Eurofins). Human DDR1/DDR2 kinase was incubated with 8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
US Patent