BDBM570180 US11427593, Compound ZB-BD-189

SMILES Cc1cc(-c2cc(ccc2OC2CCCCC2)S(C)(=O)=O)n2cc[nH]c(=O)c12

InChI Key InChIKey=PKAMKPWWUYYJCM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 570180   

TargetBromodomain-containing protein 4 [49-170](Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM570180(US11427593, Compound ZB-BD-189)
Affinity DataIC50: 11.6nMAssay Description:AlphaScreen kit (Perkin Elmer) was used to detect effect of the compounds on binding of BRD4 bromodomain to acetylated histone H4 polypeptide. The br...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
US Patent