BDBM570440 (S) N-(6-(4-(2-Amino-2-oxoethyl)piperazin-1-yl)-2-(hydroxymethyl)-2-methyl-2,3-dihydrofuro[2,3-b]pyridin-5-yl)-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide::US11434250, Example 15::US11434250, Example 16

SMILES Cc1cnc2c(cnn2c1)C(=O)Nc1cc2C[C@](C)(CO)Oc2nc1N1CCN(CC(N)=O)CC1

InChI Key InChIKey=JOHXLJCCDLLMLY-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 570440   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Genentech

US Patent
LigandPNGBDBM570440(US11434250, Example 16 | (S) N-(6-(4-(2-Amino-2-ox...)
Affinity DataKi:  5.5nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2022
Entry Details
Go to US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Genentech

US Patent
LigandPNGBDBM570440(US11434250, Example 16 | (S) N-(6-(4-(2-Amino-2-ox...)
Affinity DataKi:  6.60nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2022
Entry Details
Go to US Patent