BDBM570932 US11440904, Compound 32

SMILES CN([C@H]1[C@@H](Cc2ccccc12)Oc1nc(Nc2ccc3OCCOCCOCCOc3c2)ncc1C(F)(F)F)S(C)(=O)=O

InChI Key InChIKey=PCZQXHQZANIUQP-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 570932   

TargetFocal adhesion kinase 1(Human)
Milstein Zhang & Wu

US Patent
LigandPNGBDBM570932(US11440904, Compound 32)
Affinity DataIC50: 4.96nMAssay Description:The inhibiting activities of each of Compound-1 to Compound-24 against BTK wt, BTK(C481S), BMX, FAK, ITK, and EGFR wt kinases were determined using 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Milstein Zhang & Wu

US Patent
LigandPNGBDBM570932(US11440904, Compound 32)
Affinity DataIC50: 4.96nMAssay Description:The inhibiting activities of each of Compound-1 to Compound-24 against BTK wt, BTK(C481S), BMX, FAK, ITK, and EGFR wt kinases were determined using 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Milstein Zhang & Wu

US Patent
LigandPNGBDBM570932(US11440904, Compound 32)
Affinity DataIC50: 4.96nMAssay Description:The inhibiting activities of each of Compound-1 to Compound-24 against BTK wt, BTK(C481S), BMX, FAK, ITK, and EGFR wt kinases were determined using 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Milstein Zhang & Wu

US Patent
LigandPNGBDBM570932(US11440904, Compound 32)
Affinity DataIC50: 1.00E+3nMAssay Description:The inhibiting activities of each of Compound-1 to Compound-24 against BTK wt, BTK(C481S), BMX, FAK, ITK, and EGFR wt kinases were determined using 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Milstein Zhang & Wu

US Patent
LigandPNGBDBM570932(US11440904, Compound 32)
Affinity DataIC50: 1.00E+3nMAssay Description:The inhibiting activities of each of Compound-1 to Compound-24 against BTK wt, BTK(C481S), BMX, FAK, ITK, and EGFR wt kinases were determined using 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Milstein Zhang & Wu

US Patent
LigandPNGBDBM570932(US11440904, Compound 32)
Affinity DataIC50: 1.00E+3nMAssay Description:The inhibiting activities of each of Compound-1 to Compound-24 against BTK wt, BTK(C481S), BMX, FAK, ITK, and EGFR wt kinases were determined using 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Milstein Zhang & Wu

US Patent
LigandPNGBDBM570932(US11440904, Compound 32)
Affinity DataIC50: 1.00E+4nMAssay Description:The inhibiting activities of each of Compound-1 to Compound-24 against BTK wt, BTK(C481S), BMX, FAK, ITK, and EGFR wt kinases were determined using 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Milstein Zhang & Wu

US Patent
LigandPNGBDBM570932(US11440904, Compound 32)
Affinity DataIC50: 1.00E+4nMAssay Description:The inhibiting activities of each of Compound-1 to Compound-24 against BTK wt, BTK(C481S), BMX, FAK, ITK, and EGFR wt kinases were determined using 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Milstein Zhang & Wu

US Patent
LigandPNGBDBM570932(US11440904, Compound 32)
Affinity DataIC50: 1.00E+4nMAssay Description:The inhibiting activities of each of Compound-1 to Compound-24 against BTK wt, BTK(C481S), BMX, FAK, ITK, and EGFR wt kinases were determined using 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
US Patent