BDBM57212 4,6,7-tris(4-chlorophenyl)-2-sulfanylidene-3,4,7,8-tetrahydro-1H-pyrimido[4,5-d]pyrimidin-5-one::4,6,7-tris(4-chlorophenyl)-2-thioxo-3,4,7,8-tetrahydro-1H-pyrimido[4,5-d]pyrimidin-5-one::MLS000536083::SMR000155440::cid_5005059

SMILES Clc1ccc(cc1)C1NC(=S)N=C2NC(N(C(=O)C12)c1ccc(Cl)cc1)c1ccc(Cl)cc1

InChI Key InChIKey=UYOLVCDCNXOLBF-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 57212   

TargetMelanocortin receptor 4(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM57212(SMR000155440 | cid_5005059 | 4,6,7-tris(4-chloroph...)
Affinity DataEC50:  9.63E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRISMC) Center Affiliation: The Scripps Research Institute, TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2012
Entry Details
PCBioAssay
TargetDelta-type opioid receptor(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM57212(SMR000155440 | cid_5005059 | 4,6,7-tris(4-chloroph...)
Affinity DataEC50:  2.98E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRISMC) Center Affiliation: The Scripps Research Institute, TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2012
Entry Details
PCBioAssay
TargetStreptokinase A(Streptococcus pyogenes M1 GAS)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM57212(SMR000155440 | cid_5005059 | 4,6,7-tris(4-chloroph...)
Affinity DataEC50:  1.50E+5nMAssay Description:Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2011
Entry Details
PCBioAssay
TargetHeat shock factor protein 1(Mouse)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM57212(SMR000155440 | cid_5005059 | 4,6,7-tris(4-chloroph...)
Affinity DataEC50: >2.60E+5nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2011
Entry Details
PCBioAssay