BDBM574464 (R)-5-(1-(2,3-dihydrobenzofuran-6-yl)ethyl)-2-phenyl-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridine and (S)-5-(1-(2,3-dihydrobenzofuran-6-yl)ethyl)-2-phenyl-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridine::US11458140, Example 12::US11458140, Example 13

SMILES CC(N1CCc2nn(cc2C1)-c1ccccc1)c1ccc2CCOc2c1

InChI Key InChIKey=MMDYKVPOQPODMW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 574464   

TargetProtein O-GlcNAcase(Human)
Asceneuron

US Patent
LigandPNGBDBM574464(US11458140, Example 12 | (R)-5-(1-(2,3-dihydrobenz...)
Affinity DataIC50: 125nMAssay Description:5 μl of the appropriate concentration of a solution of inhibitor in McIlvaine's Buffer (pH 6.5) in 2% DMSO (for a dose response curve calcul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Asceneuron

US Patent
LigandPNGBDBM574464(US11458140, Example 12 | (R)-5-(1-(2,3-dihydrobenz...)
Affinity DataIC50: 5.50E+3nMAssay Description:5 μl of the appropriate concentration of a solution of inhibitor in McIlvaine's Buffer (pH 6.5) in 2% DMSO (for a dose response curve calcul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent