BDBM574716 3-(Pyridin-3-yl)-1-sulfamoyl- 1H-pyrrole-2-carboxylic acid, sodium salt::US11459296, Example 8

SMILES NS(=O)(=O)n1ccc(c1C([O-])=O)-c1cccnc1

InChI Key InChIKey=LVHORGWLLDUFME-UHFFFAOYSA-M

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 574716   

TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
Infex Therapeutics

US Patent
LigandPNGBDBM574716(US11459296, Example 8 | 3-(Pyridin-3-yl)-1-sulfamo...)
Affinity DataIC50: 448nMAssay Description:Inhibition of metallo-β-lactamase enzyme function was performed at 37° C. in buffer at pH 7.5 (50 mM HEPES, 150 mM NaCl, 0.1 mM ZnSO4, 20 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent