BDBM574723 3-(6-Amino-5-fluoro-3- pyridyl)-1-sulfamoyl-pyrrole- 2-carboxylic acid::US11459296, Example 21

SMILES Nc1ncc(cc1F)-c1ccn(c1C(O)=O)S(N)(=O)=O

InChI Key InChIKey=LETNQMCESTVGDW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 574723   

TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
Infex Therapeutics

US Patent
LigandPNGBDBM574723(US11459296, Example 21 | 3-(6-Amino-5-fluoro-3- py...)
Affinity DataIC50: 3.36E+3nMAssay Description:Inhibition of metallo-β-lactamase enzyme function was performed at 37° C. in buffer at pH 7.5 (50 mM HEPES, 150 mM NaCl, 0.1 mM ZnSO4, 20 μ...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2022
Entry Details
US Patent