BDBM574730 (hydrochloride salt): 3-[4-(Piperidin-4-yl)phenyl]-1-sulfamoyl-1H-pyrrole-2-carboxylic acid hydrochloride::US11459296, Example 34

SMILES NS(=O)(=O)n1ccc(c1C(O)=O)-c1ccc(cc1)C1CC[NH2+]CC1

InChI Key InChIKey=SYMAXUCOVKFWPD-UHFFFAOYSA-O

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 574730   

TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
Infex Therapeutics

US Patent
LigandPNGBDBM574730(US11459296, Example 34 | (hydrochloride salt): 3-[...)
Affinity DataIC50: 151nMAssay Description:Inhibition of metallo-β-lactamase enzyme function was performed at 37° C. in buffer at pH 7.5 (50 mM HEPES, 150 mM NaCl, 0.1 mM ZnSO4, 20 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent