BDBM574733 US11459296, Example 46

SMILES Cn1c([NH3+])nc2c(cccc12)-c1ccn(c1C(O)=O)S(N)(=O)=O

InChI Key InChIKey=RSHRWQCGCFLKNH-UHFFFAOYSA-O

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 574733   

TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
Infex Therapeutics

US Patent
LigandPNGBDBM574733(US11459296, Example 46)
Affinity DataIC50: 2.79E+3nMAssay Description:Inhibition of metallo-β-lactamase enzyme function was performed at 37° C. in buffer at pH 7.5 (50 mM HEPES, 150 mM NaCl, 0.1 mM ZnSO4, 20 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent