BDBM574735 (Hydrochloride Salt): 3-[4-(3-Aminopropylcarbamoyl)phenyl]-1-sulfamoyl-pyrrole-2-carboxylic acid hydrochloride::US11459296, Example 51

SMILES NS(=O)(=O)n1ccc(c1C(O)=O)-c1ccc(cc1)C(=O)NCCC[NH3+]

InChI Key InChIKey=PELVOFFKOIIKHO-UHFFFAOYSA-O

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 574735   

TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
Infex Therapeutics

US Patent
LigandPNGBDBM574735(US11459296, Example 51 | (Hydrochloride Salt): 3-[...)
Affinity DataIC50: 263nMAssay Description:Inhibition of metallo-β-lactamase enzyme function was performed at 37° C. in buffer at pH 7.5 (50 mM HEPES, 150 mM NaCl, 0.1 mM ZnSO4, 20 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent