BDBM574744 3-(6-Aminopyridin-3-yl)-2- (1H-tetrazol-5-yl)-1H- pyrrole-1-sulfonamide::US11459296, Example 77

SMILES Nc1ccc(cn1)-c1ccn(c1-c1nnn[nH]1)S(N)(=O)=O

InChI Key InChIKey=PFTOOWBGNWIGAB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 574744   

TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
Infex Therapeutics

US Patent
LigandPNGBDBM574744(US11459296, Example 77 | 3-(6-Aminopyridin-3-yl)-2...)
Affinity DataIC50: 506nMAssay Description:Inhibition of metallo-β-lactamase enzyme function was performed at 37° C. in buffer at pH 7.5 (50 mM HEPES, 150 mM NaCl, 0.1 mM ZnSO4, 20 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent