BDBM575217 3-[[6-[3-(Difluoromethyl)-4-fluoro-phenyl]pyrazin-2- yl]methyl]oxazolidin-2-one::US11459336, Example 1

SMILES FC(F)c1cc(ccc1F)-c1cncc(CN2CCOC2=O)n1

InChI Key InChIKey=XLEKQFXQIUWWBZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575217   

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM575217(US11459336, Example 1 | 3-[[6-[3-(Difluoromethyl)-...)
Affinity DataIC50: 195nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent