BDBM575366 US11459335, Degronimer 2::US20230279023, Compound Degronimer 2

SMILES Cc1nnc2n1-c1ccc(cc1C(=NC21CC1)c1ccc(Cl)cc1)-c1cnn(CCCCCCN2CCN(CC2)c2ccc(NC3CCC(=O)NC3=O)cc2)c1

InChI Key InChIKey=CYZNLZCEQIHJMZ-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 575366   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM575366(US11459335, Degronimer 2 | US20230279023, Compound...)
Affinity DataKd: <1.00E+4nMAssay Description:Measuring compound ligand binding to CRBN-DDB1 was carried out using an established sensitive and quantitative in vitro fluorescence polarization (FP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
US Patent

TargetDNA damage-binding protein 1/Protein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM575366(US11459335, Degronimer 2 | US20230279023, Compound...)
Affinity DataKd: <1.00E+4nMAssay Description:Measuring compound ligand binding to CRBN-DDB1 was carried out using an established sensitive and quantitative in vitro fluorescence polarization (FP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent