BDBM575368 5-[[6-[3-(Difluoromethyl)-4-fluoro-phenyl]pyrazin-2- yl]methyl]-7-oxa-5-azaspiro[2.4]heptan-6-one::US11459336, Example 3

SMILES FC(F)c1cc(ccc1F)-c1cncc(CN2CC3(CC3)OC2=O)n1

InChI Key InChIKey=KZMPDDVHWIESKP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575368   

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM575368(US11459336, Example 3 | 5-[[6-[3-(Difluoromethyl)-...)
Affinity DataIC50: 13nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent