BDBM575377 (4S)-3-[[6-[3-(Difluoromethyl)-4-fluoro-phenyl]-3-methyl- pyrazin-2-yl]methyl]-4-methyl-oxazolidin-2-one::US11459336, Example 12

SMILES C[C@H]1COC(=O)N1Cc1nc(cnc1C)-c1ccc(F)c(c1)C(F)F

InChI Key InChIKey=NABQDFIWOVWIHA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575377   

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM575377(US11459336, Example 12 | (4S)-3-[[6-[3-(Difluorome...)
Affinity DataIC50: 605nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent