BDBM575430 (R/S)-3-[[6-[3-(Difluoromethoxy)-4-fluoro-phenyl]pyrazin-2- yl]methyl]-N,N-dimethyl-2-oxo-oxazolidine-5-carboxamide::US11459336, Example 66

SMILES CN(C)C(=O)C1CN(Cc2cncc(n2)-c2ccc(F)c(OC(F)F)c2)C(=O)O1

InChI Key InChIKey=MSNNRWVFFQTTLI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575430   

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM575430(US11459336, Example 66 | (R/S)-3-[[6-[3-(Difluorom...)
Affinity DataIC50: 141nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent