BDBM575431 64[6-[4-Chloro-3-(difluoromethoxy)phenyl]pyrazin-2- yl]methyl]-8-oxa-2,6-diazaspiro[3.4]octan-7-one::US11459336, Example 67

SMILES FC(F)Oc1cc(ccc1Cl)-c1cncc(CN2CC3(CNC3)OC2=O)n1

InChI Key InChIKey=QWBSMGVELKDPIS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575431   

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM575431(US11459336, Example 67 | 64[6-[4-Chloro-3-(difluor...)
Affinity DataIC50: 530nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent