BDBM575432 64[6-[4-Chloro-3-(difluoromethoxy)phenyl]pyrazin-2- yl]methyl]-2-methyl-8-oxa-2,6-diazaspiro[3.4]octan-7-one::US11459336, Example 68

SMILES CN1CC2(C1)CN(Cc1cncc(n1)-c1ccc(Cl)c(OC(F)F)c1)C(=O)O2

InChI Key InChIKey=PUOSICQCSZJYPF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575432   

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM575432(US11459336, Example 68 | 64[6-[4-Chloro-3-(difluor...)
Affinity DataIC50: 599nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2022
Entry Details
US Patent