BDBM575478 US11459337, Compound WX058

SMILES CN(C)C1CCN(CC1)[C@H]1CC[C@@H](CC1)Nc1nc(Nc2cnn(c2)C2CCOCC2)nc2snc(C)c12

InChI Key InChIKey=QKRYNMVSMQKHCL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575478   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM575478(US11459337, Compound WX058)
Affinity DataIC50: 2.10nMAssay Description:The inhibitory activity of the test compounds against human IRAK4 was evaluated by measuring IC50 values in a 33P-labeled kinase activity assay (Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent