BDBM575651 US11464802, Compound 20
SMILES Cn1cnnc1CC1(COC1)c1cccc(c1)N1Cc2c(cc(CN3C[C@H](C[C@@H](C3)C(F)(F)F)C(F)(F)F)cc2C(F)(F)F)C1=O
InChI Key InChIKey=QYIPFMFUPYQZID-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 575651
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Human)
Nurix Therapeutics
US Patent
Nurix Therapeutics
US Patent
Affinity DataIC50: 3nMAssay Description:Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 46). Cbl-b displacement assays were performed in a 384-well ...More data for this Ligand-Target Pair
