BDBM575734 2-(2-chloropyridin- 3-yl)-1-(7- fluoro-5-(2-((4- hydroxylcyclohexyl) amino)pyrimidin- 4-yl)indolin-1-yl) ethan-1-one::US11465984, Example P3

SMILES OC1CCC(CC1)Nc1nccc(n1)-c1cc2CCN(C(=O)Cc3cccnc3Cl)c2c(F)c1

InChI Key InChIKey=JJWBXAKDVDNPKT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575734   

TargetMitogen-activated protein kinase 1(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM575734(US11465984, Example P3 | 2-(2-chloropyridin- 3-yl)...)
Affinity DataIC50: 55nMAssay Description:The substrate Z′-LYTE Ser/Thr 3 Peptide, the phosphorylation substrate Z′-LYTE Ser/Thr 3 Phospho-peptide, 1× kinase buffer (5× kinase buf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent