BDBM575739 2-(2-chloropyridin-3-yl)-1-(7-fluoro-5-(2-((1-hydroxylprop-2-yl)amino)pyridin-4-yl)indolin-1-yl)ethan-1-one (P8)::US11465984, Example P8

SMILES CC(CO)Nc1cc(ccn1)-c1cc2CCN(C(=O)Cc3cccnc3Cl)c2c(F)c1

InChI Key InChIKey=ZTCZYXHLZDINHB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575739   

TargetMitogen-activated protein kinase 1(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM575739(US11465984, Example P8 | 2-(2-chloropyridin-3-yl)-...)
Affinity DataIC50: 550nMAssay Description:The substrate Z′-LYTE Ser/Thr 3 Peptide, the phosphorylation substrate Z′-LYTE Ser/Thr 3 Phospho-peptide, 1× kinase buffer (5× kinase buf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent