BDBM575740 2-(2-chloropyridin-3-yl)-1-(7-fluoro-5-(2-((1-methyl-1H-pyrazol-5-yl)amino)pyridin-4-yl)indolin-1-yl)ethan-1-one (P9)::US11465984, Example P46::US11465984, Example P9

SMILES Cn1nccc1Nc1cc(ccn1)-c1cc2CCN(C(=O)Cc3cccnc3Cl)c2c(F)c1

InChI Key InChIKey=MFTHIZDCYXUNAM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 575740   

TargetMitogen-activated protein kinase 1(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM575740(US11465984, Example P9 | 2-(2-chloropyridin-3-yl)-...)
Affinity DataIC50: 3.30nMAssay Description:The substrate Z′-LYTE Ser/Thr 3 Peptide, the phosphorylation substrate Z′-LYTE Ser/Thr 3 Phospho-peptide, 1× kinase buffer (5× kinase buf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM575740(US11465984, Example P9 | 2-(2-chloropyridin-3-yl)-...)
Affinity DataIC50: 10nMAssay Description:The substrate Z′-LYTE Ser/Thr 3 Peptide, the phosphorylation substrate Z′-LYTE Ser/Thr 3 Phospho-peptide, 1× kinase buffer (5× kinase buf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent