BDBM575743 2-(2,4- difluorophenyl)- 1-(7-fluoro-5- (2-((1-methyl- 1H-pyrazol-5- yl)amino) pyrimidin- 4-yl)indolin-1- yl)ethan-1-one::US11465984, Example P12

SMILES Cn1nccc1Nc1nccc(n1)-c1cc2CCN(C(=O)Cc3ccc(F)cc3F)c2c(F)c1

InChI Key InChIKey=BRCYQVAAGNZQMJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575743   

TargetMitogen-activated protein kinase 1(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM575743(US11465984, Example P12 | 2-(2,4- difluorophenyl)-...)
Affinity DataIC50: 55nMAssay Description:The substrate Z′-LYTE Ser/Thr 3 Peptide, the phosphorylation substrate Z′-LYTE Ser/Thr 3 Phospho-peptide, 1× kinase buffer (5× kinase buf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent