BDBM575744 2-(2- chloropyridin-3- yl)-1-(7-methyl- 5-(2-((1-methyl- 1H-pyrazol-5- yl)amino) pyrimidin- 4-yl)indolin- 1-yl)ethan-1- one::US11465984, Example P13

SMILES Cc1cc(cc2CCN(C(=O)Cc3cccnc3Cl)c12)-c1ccnc(Nc2ccnn2C)n1

InChI Key InChIKey=FTJWBLLXOWPPOF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575744   

TargetMitogen-activated protein kinase 1(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM575744(US11465984, Example P13 | 2-(2- chloropyridin-3- y...)
Affinity DataIC50: 550nMAssay Description:The substrate Z′-LYTE Ser/Thr 3 Peptide, the phosphorylation substrate Z′-LYTE Ser/Thr 3 Phospho-peptide, 1× kinase buffer (5× kinase buf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent