BDBM575751 2-(2-(7-fluoro-5- (2-((1-methyl-1H- pyrazol-5-yl) amino)pyrimidin- 4-yl)indolin-1-yl)- 2-oxoethyl) benzonitrile::US11465984, Example P30

SMILES Cn1nccc1Nc1nccc(n1)-c1cc2CCN(C(=O)Cc3ccccc3C#N)c2c(F)c1

InChI Key InChIKey=WJPGFEOPSXNYCA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575751   

TargetMitogen-activated protein kinase 1(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM575751(US11465984, Example P30 | 2-(2-(7-fluoro-5- (2-((1...)
Affinity DataIC50: 55nMAssay Description:The substrate Z′-LYTE Ser/Thr 3 Peptide, the phosphorylation substrate Z′-LYTE Ser/Thr 3 Phospho-peptide, 1× kinase buffer (5× kinase buf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent