BDBM575753 2-(2- chloropyridin-3- yl)-1-(7-fluoro- 2-methyl-5-(2- ((1-methyl-1H- pyrazol-5-yl) amino) pyrimidin- 4-yl)indolin-1- yl)ethan-1-one::US11465984, Example P32

SMILES CC1Cc2cc(cc(F)c2N1C(=O)Cc1cccnc1Cl)-c1ccnc(Nc2ccnn2C)n1

InChI Key InChIKey=ZJBAULBXPFNWPE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575753   

TargetMitogen-activated protein kinase 1(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM575753(US11465984, Example P32 | 2-(2- chloropyridin-3- y...)
Affinity DataIC50: 10nMAssay Description:The substrate Z′-LYTE Ser/Thr 3 Peptide, the phosphorylation substrate Z′-LYTE Ser/Thr 3 Phospho-peptide, 1× kinase buffer (5× kinase buf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent