BDBM575754 2-(2-chloro-4- fluoropyridin-3-yl)- 1-(7-fluoro-5- (2-((1-methyl-1H- pyrazol-5-yl) amino)pyrimidin- 4-yl)indolin-1-yl) ethan-1-one::US11465984, Example P33

SMILES Cn1nccc1Nc1nccc(n1)-c1cc2CCN(C(=O)Cc3c(F)ccnc3Cl)c2c(F)c1

InChI Key InChIKey=YIRLZNNALUGEBR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575754   

TargetMitogen-activated protein kinase 1(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM575754(US11465984, Example P33 | 2-(2-chloro-4- fluoropyr...)
Affinity DataIC50: 55nMAssay Description:The substrate Z′-LYTE Ser/Thr 3 Peptide, the phosphorylation substrate Z′-LYTE Ser/Thr 3 Phospho-peptide, 1× kinase buffer (5× kinase buf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent