BDBM575769 2-(2-chloropyridin- 3-yl)-1-(7-fluoro- 2-methyl-5-(5- methyl-2-((1- methyl-1H-pyrazol- 5-yl)amino) pyrimidin-4-yl) indolin-1-yl)ethan- 1-one::US11465984, Example P48

SMILES CC1Cc2cc(cc(F)c2N1C(=O)Cc1cccnc1Cl)-c1nc(Nc2ccnn2C)ncc1C

InChI Key InChIKey=NQHQXESLYHSBLY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575769   

TargetMitogen-activated protein kinase 1(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM575769(US11465984, Example P48 | 2-(2-chloropyridin- 3-yl...)
Affinity DataIC50: 10nMAssay Description:The substrate Z′-LYTE Ser/Thr 3 Peptide, the phosphorylation substrate Z′-LYTE Ser/Thr 3 Phospho-peptide, 1× kinase buffer (5× kinase buf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent