BDBM575771 2-(2-chloropyridin- 3-yl)-1-(4,7- difluoro-5-(2-((1- methyl-1H- pyrazol-5-yl)amino) pyrimidin-4-yl) indolin-1-yl)ethan- 1-one::US11465984, Example P50

SMILES Cn1nccc1Nc1nccc(n1)-c1cc(F)c2N(CCc2c1F)C(=O)Cc1cccnc1Cl

InChI Key InChIKey=IJQSWXUDTQKGDS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575771   

TargetMitogen-activated protein kinase 1(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM575771(US11465984, Example P50 | 2-(2-chloropyridin- 3-yl...)
Affinity DataIC50: 550nMAssay Description:The substrate Z′-LYTE Ser/Thr 3 Peptide, the phosphorylation substrate Z′-LYTE Ser/Thr 3 Phospho-peptide, 1× kinase buffer (5× kinase buf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent