BDBM575773 2-(2-chloro-3- fluorophenyl)-1- (7-fluoro-5-(2-((1- methyl-1H-pyrazol- 5-yl)amino) pyrimidin-4-yl) indolin-1-yl)ethan- 1-one::US11465984, Example P54

SMILES Cn1nccc1Nc1nccc(n1)-c1cc2CCN(C(=O)Cc3cccc(F)c3Cl)c2c(F)c1

InChI Key InChIKey=XHEWLULHSDFYDL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575773   

TargetMitogen-activated protein kinase 1(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM575773(US11465984, Example P54 | 2-(2-chloro-3- fluorophe...)
Affinity DataIC50: 55nMAssay Description:The substrate Z′-LYTE Ser/Thr 3 Peptide, the phosphorylation substrate Z′-LYTE Ser/Thr 3 Phospho-peptide, 1× kinase buffer (5× kinase buf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent