BDBM575777 2-(2-chloropyridin- 3-yl)-1-(7-fluoro-2- (methoxymethyl)-5- (2-((1-methyl-1H- pyrazol-5-yl) amino)pyridin-4-yl) indolin-1-yl)ethan- 1-one::US11465984, Example P58

SMILES COCC1Cc2cc(cc(F)c2N1C(=O)Cc1cccnc1Cl)-c1ccnc(Nc2ccnn2C)c1

InChI Key InChIKey=XBVPGPYUHPENDZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575777   

TargetMitogen-activated protein kinase 1(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM575777(US11465984, Example P58 | 2-(2-chloropyridin- 3-yl...)
Affinity DataIC50: 10nMAssay Description:The substrate Z′-LYTE Ser/Thr 3 Peptide, the phosphorylation substrate Z′-LYTE Ser/Thr 3 Phospho-peptide, 1× kinase buffer (5× kinase buf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent