BDBM575819 US11466003, Compound 38

SMILES Cc1nc(ccc1F)-c1ccccc1-c1ccc2ncc(C(N)=O)n2c1

InChI Key InChIKey=MXFWXKVWTGFVQZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575819   

TargetTGF-beta receptor type-1(Human)
Shanghai Yingli Pharmaceutical

US Patent
LigandPNGBDBM575819(US11466003, Compound 38)
Affinity DataIC50: 18nMAssay Description:1. Preparation of kinase buffer: 40 mM Tris (pH 7.5), 20 mM MgCl2, 0.10% BSA, 1 mM DTT.2. Preparation of the compound: the final concentration of the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent