BDBM576090 4-(6-(4-(1-Aminoethyl)-4-methylpiperidin-1-yl)-1H-pyrazolo[3,4-b]pyrazin-3-yl)-3-chloropyridin-2-amine::US11466017, Example 113a

SMILES C[C@@H](N)C1(C)CCN(CC1)c1cnc2c(n[nH]c2n1)-c1ccnc(N)c1Cl

InChI Key InChIKey=QYFJZZVWAJSRBH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 576090   

TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Human)
University Of Texas

US Patent
LigandPNGBDBM576090(US11466017, Example 113a | 4-(6-(4-(1-Aminoethyl)-...)
Affinity DataIC50: 180nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
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