BDBM576123 2-amino-9-[(5S,7R,8R,12aR,14R,15aS)- 14-(4-aminoimidazo[2,1-f][1,2,4]triazin-7- yl)-10-hydroxy-2-sulfanyl-2,10- disulfidooctahydro-12H-5,8- methanofuro[3,2-1][1,3,6,9,11,2,10]penta- oxadiphosphacyclotetradecin-7-yl]-1,9- dihydro-6H-purin-6-one (Diastereomer 1)::US11466047, Example 7::US11466047, Example 8

SMILES Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@H]2C[C@H]1OP(O)(=S)OC[C@H]1O[C@H](C[C@@H]1OP(S)(=S)OC2)c1cnc2c(N)ncnn12

InChI Key InChIKey=KZMUIJRMEXUBNL-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 576123   

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM576123(US11466047, Example 7 | 2-amino-9-[(5S,7R,8R,12aR,...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM576123(US11466047, Example 7 | 2-amino-9-[(5S,7R,8R,12aR,...)
Affinity DataEC50:  7nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent