BDBM576243 WO2022109580, Example 2

SMILES CO[C@@]1(CCOC1)c1cc(C)cc(n1)-n1nc(-c2cnn(C)c2)c2cnc(NC(N)=O)cc12

InChI Key InChIKey=SXVDLZBWXAYZHZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 576243   

TargetNon-receptor tyrosine-protein kinase TYK2 [556-871](Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM576243(WO2022109580, Example 2)
Affinity DataIC50: 4nMAssay Description:The probe displacement assay is conducted as follows: In a 384-well plate, test compound along with recombinantly expressed His-tagged protein corres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2022
Entry Details
WIPO WO2022109580