BDBM576249 WO2022109580, Example 10

SMILES COCCOc1cc(nc(c1)[C@]1(CCOC1)OC)-n1nc(C)c2cnc(NC(N)=O)cc12

InChI Key InChIKey=ZITPGMGHRIFONJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 576249   

TargetNon-receptor tyrosine-protein kinase TYK2 [556-871](Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM576249(WO2022109580, Example 10)
Affinity DataIC50: 6nMAssay Description:The probe displacement assay is conducted as follows: In a 384-well plate, test compound along with recombinantly expressed His-tagged protein corres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2022
Entry Details
WIPO WO2022109580