BDBM576260 WO2022109580, Example 23

SMILES CO[C@@]5(c4cc(C)cc(N3C=C(c1cnn(C)c1)N2C=NC(NC(N)=O)=CC23)n4)CCOC5

InChI Key InChIKey=NKSOSYSWFRBYJV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 576260   

TargetNon-receptor tyrosine-protein kinase TYK2 [556-871](Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM576260(WO2022109580, Example 23)
Affinity DataIC50: 5nMAssay Description:The probe displacement assay is conducted as follows: In a 384-well plate, test compound along with recombinantly expressed His-tagged protein corres...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/14/2022
Entry Details
WIPO WO2022109580