BDBM576262 WO2022109580, Example 25

SMILES CO[C@]4(c3cc(C)cc(c1cc(C)n2cnc(NC(N)=O)cc12)n3)CCOC4

InChI Key InChIKey=KCNDGFPTNZEEGQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 576262   

TargetNon-receptor tyrosine-protein kinase TYK2 [556-871](Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM576262(WO2022109580, Example 25)
Affinity DataIC50: 2nMAssay Description:The probe displacement assay is conducted as follows: In a 384-well plate, test compound along with recombinantly expressed His-tagged protein corres...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/14/2022
Entry Details
WIPO WO2022109580