BDBM576416 (R or S)-2-(1-Cyclopropyl-2-hydroxy-2-methylpropyl)-6-fluoro- 7-(4-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl)isoindolin-1-one::WO2022115301, Example 2

SMILES Cc1nnc(o1)-c1ccc(cc1)-c1c2C(=O)N(Cc2ccc1F)C(C1CC1)C(C)(C)O

InChI Key InChIKey=FYLTWYACRCCBDC-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 576416   

TargetCeramide glucosyltransferase(Human)
Merck Sharp &Amp

WIPO
LigandPNGBDBM576416(WO2022115301, Example 2 | (R or S)-2-(1-Cyclopropy...)
Affinity DataEC50:  2.60nMAssay Description: Using Promega s UDP-Glo Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2022
Entry Details
WIPO WO2022115301