BDBM576587 (E)-2-(((4-((2-(aminomethyl)-3- fluoroallyl)oxy)phenyl)sulfonyl) methyl)isoindolin-1-one::US11472769, Compound 118

SMILES NC\C(COc1ccc(cc1)S(=O)(=O)CN1Cc2ccccc2C1=O)=C/F

InChI Key InChIKey=UVBLTDMIYPKNHZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 576587   

TargetAmine oxidase [copper-containing] 2(Human)
Eccogene (Shanghai)

US Patent
LigandPNGBDBM576587(US11472769, Compound 118 | (E)-2-(((4-((2-(aminome...)
Affinity DataIC50: 60nMAssay Description:Amine oxidase activity of recombinant hSSAO, hMAO-A, and hMAO-B isoforms are measured using the MAO-Glo assay kit (Promega, V1402). Ten nL test compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2022
Entry Details
US Patent

TargetAmine oxidase [flavin-containing] A(Human)
Eccogene (Shanghai)

US Patent
LigandPNGBDBM576587(US11472769, Compound 118 | (E)-2-(((4-((2-(aminome...)
Affinity DataIC50: 1.00E+4nMAssay Description:Amine oxidase activity of recombinant hSSAO, hMAO-A, and hMAO-B isoforms are measured using the MAO-Glo assay kit (Promega, V1402). Ten nL test compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2022
Entry Details
US Patent

TargetAmine oxidase [flavin-containing] B(Human)
Eccogene (Shanghai)

US Patent
LigandPNGBDBM576587(US11472769, Compound 118 | (E)-2-(((4-((2-(aminome...)
Affinity DataIC50: 1.00E+4nMAssay Description:Amine oxidase activity of recombinant hSSAO, hMAO-A, and hMAO-B isoforms are measured using the MAO-Glo assay kit (Promega, V1402). Ten nL test compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2022
Entry Details
US Patent