BDBM576705 US11472782, Compound I-76

SMILES COC(=O)C(C)(C)C#Cc1ccc2OCC(NC(=O)c3n[nH]c(Cc4ccccc4)n3)C(=O)N(C)c2c1

InChI Key InChIKey=GSPCYRDEQOOAAN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 576705   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM576705(US11472782, Compound I-76)
Affinity DataIC50: 44.9nMAssay Description:ADP-Glo (Promega, Madison, Wis., USA) reagents were thawed at ambient temperature. Kinase Detection Reagent was prepared by mixing kinase detection b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2022
Entry Details
US Patent