BDBM576706 US11472782, Compound I-77

SMILES CN1c2cc(ccc2OCC(NC(=O)c2ccn(Cc3ccccc3)n2)C1=O)C#CC(C)(C)O

InChI Key InChIKey=FHGVKOISIPVSNG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 576706   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM576706(US11472782, Compound I-77)
Affinity DataIC50: 32.7nMAssay Description:ADP-Glo (Promega, Madison, Wis., USA) reagents were thawed at ambient temperature. Kinase Detection Reagent was prepared by mixing kinase detection b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2022
Entry Details
US Patent