BDBM576801 N-((3R,4S)-1- (Cyclopropylsulfonyl)-3- fluoropiperidin-4-yl)-4- (1-(2-methyl-4- ((methylamino)methyl) phenyl)-1H-pyrazol-4-yl)-5- (trifluoromethyl)pyrimidin- 2-amine::US11472791, Example 123::US11472791, Example 133

SMILES CNCc1ccc(c(C)c1)-n1cc(cn1)-c1nc(N[C@H]2CCN(C[C@H]2F)S(=O)(=O)C2CC2)ncc1C(F)(F)F

InChI Key InChIKey=GYYLCYUJCIIJBM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 576801   

LigandPNGBDBM576801(US11472791, Example 123 | N-((3R,4S)-1- (Cycloprop...)
Affinity DataIC50: 50nMAssay Description:CDK2/Cyclin E1 enzyme activity assays utilize full-length human CDK2 co-expressed as N-terminal GST-tagged protein with FLAG-Cyclin E1 in a baculovir...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2022
Entry Details
US Patent

LigandPNGBDBM576801(US11472791, Example 123 | N-((3R,4S)-1- (Cycloprop...)
Affinity DataIC50: 50nMAssay Description:CDK2/Cyclin E1 enzyme activity assays utilize full-length human CDK2 co-expressed as N-terminal GST-tagged protein with FLAG-Cyclin E1 in a baculovir...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2022
Entry Details
US Patent