BDBM577155 3-(8-Cyclopropyl-9-oxo-6,7,8,9-tetrahydropyrido[2',3':4,5]pyrrolo[1,2-a]pyrazin-10-yl)-4-methylbenzonitrile::US11472805, Example 60

SMILES Cc1ccc(cc1-c1c2C(=O)N(CCn2c2cccnc12)C1CC1)C#N

InChI Key InChIKey=DNQXAUUOWTUBLN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 577155   

LigandPNGBDBM577155(US11472805, Example 60 | 3-(8-Cyclopropyl-9-oxo-6,...)
Affinity DataIC50: 11.2nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

LigandPNGBDBM577155(US11472805, Example 60 | 3-(8-Cyclopropyl-9-oxo-6,...)
Affinity DataIC50: 11.8nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

LigandPNGBDBM577155(US11472805, Example 60 | 3-(8-Cyclopropyl-9-oxo-6,...)
Affinity DataIC50: 99nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

LigandPNGBDBM577155(US11472805, Example 60 | 3-(8-Cyclopropyl-9-oxo-6,...)
Affinity DataIC50: 397nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent