BDBM5772 4-butoxy-5-[(2-methylphenyl)carbonyl]-1H-pyrazolo[3,4-b]pyridine::SQ-67563 Analog 21b::pyrazolo[3,4-b]pyridine deriv.

SMILES CCCCOc1c(cnc2[nH]ncc12)C(=O)c1ccccc1C

InChI Key InChIKey=PGAYABDDVPFJMW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 5772   

LigandPNGBDBM5772(4-butoxy-5-[(2-methylphenyl)carbonyl]-1H-pyrazolo[...)
Affinity DataIC50: 410nMpH: 8.0 T: 2°CAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Bristol-Myers Squibb

LigandPNGBDBM5772(4-butoxy-5-[(2-methylphenyl)carbonyl]-1H-pyrazolo[...)
Affinity DataIC50: 730nMAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2005
Entry Details Article
PubMed