BDBM5773 4-butoxy-5-[(2-fluorophenyl)carbonyl]-1H-pyrazolo[3,4-b]pyridine::SQ-67563 Analog 21e::pyrazolo[3,4-b]pyridine deriv.

SMILES CCCCOc1c(cnc2[nH]ncc12)C(=O)c1ccccc1F

InChI Key InChIKey=DGPWUICUWDZQNV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 5773   

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Bristol-Myers Squibb

LigandPNGBDBM5773(4-butoxy-5-[(2-fluorophenyl)carbonyl]-1H-pyrazolo[...)
Affinity DataIC50: 36nMAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2005
Entry Details Article
PubMed
LigandPNGBDBM5773(4-butoxy-5-[(2-fluorophenyl)carbonyl]-1H-pyrazolo[...)
Affinity DataIC50: 360nMpH: 8.0 T: 2°CAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Bristol-Myers Squibb

LigandPNGBDBM5773(4-butoxy-5-[(2-fluorophenyl)carbonyl]-1H-pyrazolo[...)
Affinity DataIC50: 2.40E+4nMAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2005
Entry Details Article
PubMed